Salt-bridge Dynamics Control Substrate-induced Conformational Change in the Membrane Transporter GlpT
نویسندگان
چکیده
منابع مشابه
Salt-bridge dynamics control substrate-induced conformational change in the membrane transporter GlpT.
Active transport of substrates across cytoplasmic membranes is of great physiological, medical and pharmaceutical importance. The glycerol-3-phosphate (G3P) transporter (GlpT) of the E. coli inner membrane is a secondary active antiporter from the ubiquitous major facilitator superfamily that couples the import of G3P to the efflux of inorganic phosphate (P(i)) down its concentration gradient. ...
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ژورنال
عنوان ژورنال: Journal of Molecular Biology
سال: 2008
ISSN: 0022-2836
DOI: 10.1016/j.jmb.2008.03.029